https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00068-7/fulltext
Important new review for anyone dealing with nerve pain
This article summarizes a major global study on neuropathic pain treatments. It’s based on updated guidelines from the International Association for the Study of Pain and reviews both drugs and non-drug options.
I’m sharing it because it clarifies what actually works—and what doesn’t.
Conclusion:
• First-line meds: gabapentin, pregabalin, duloxetine, amitriptyline
• Safe second-line: capsaicin/lidocaine patches
• rTMS now recommended for some
• Cannabinoids, valproate, and a few others are not recommended.
